Job Description

Postdoc positions are immediately available in the laboratory of Dr. Xin Qi in the Department of Physiology & Biophysics at Case Western Reserve University School of Medicine.

The lab focuses on mitochondrial pathology in neurodegenerative diseases including Alzheimer’s, Parkinson’s, Huntington’s disease and ALS. We use a combination of in vitro cell culture, in vivo transgenic animal models and patient-derived neurons to study the mechanisms by which mitochondrial impairment contributes to neurodegeneration. Another research focus of the lab is the development of therapeutics that enhance mitochondrial function, for the treatment of human diseases. We have been using the rationally designed peptide inhibitors of protein-protein interactions and high throughput screening to identify mitochondrial functional enhancers as therapeutic options.

The successful applicant will participate in projects on elucidating the molecular basis of mitochondrial damage and metabolic dysregulation in neurodegenerative diseases. The applicants must have a PhD and/or MD degree in neuroscience, molecular biology, cell biology, pharmacology, or related field. Candidates with experience in neurodegenerative diseases are highly desired.